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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Russian Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-2106</issn><issn publication-format="electronic">2412-9100</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">108939</article-id><article-id pub-id-type="doi">10.17816/medjrf108939</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A clinical case of type II bipolar affective disorder</article-title><trans-title-group xml:lang="ru"><trans-title>Биполярное аффективное расстройство II типа: клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8034-4457</contrib-id><contrib-id contrib-id-type="spin">7532-4382</contrib-id><name-alternatives><name xml:lang="en"><surname>Osipova</surname><given-names>Natalya N.</given-names></name><name xml:lang="ru"><surname>Осипова</surname><given-names>Наталья Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Associate professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>natinen@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7028-8669</contrib-id><contrib-id contrib-id-type="spin">7477-8598</contrib-id><name-alternatives><name xml:lang="en"><surname>Aleschkina</surname><given-names>Galina A.</given-names></name><name xml:lang="ru"><surname>Алёшкина</surname><given-names>Галина Андреевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н, профессор</p></bio><email>aleshkina-ga@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4638-7461</contrib-id><contrib-id contrib-id-type="spin">7740-2176</contrib-id><name-alternatives><name xml:lang="en"><surname>Beglyankin</surname><given-names>Nikolay I.</given-names></name><name xml:lang="ru"><surname>Беглянкин</surname><given-names>Николай Игоревич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>к.м.н., профессор</p></bio><email>begnik@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Evdokimov Moscow State Medical and Dental University</institution></aff><aff><institution xml:lang="ru">Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2022</year></pub-date><volume>28</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>161</fpage><lpage>166</lpage><history><date date-type="received" iso-8601-date="2022-06-22"><day>22</day><month>06</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-07-04"><day>04</day><month>07</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Эко-Вектор"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-08-15"/></permissions><self-uri xlink:href="https://medjrf.com/0869-2106/article/view/108939">https://medjrf.com/0869-2106/article/view/108939</self-uri><abstract xml:lang="en"><p>This study presents a clinical case of bipolar affective disorder type II. Difficulties in differential diagnosis at the early disease stages are discussed. The considered clinical case reflects real psychiatric practice when the onset of the disease is identified in adolescence and associated with the impact of a traumatic situation. Disease manifestations are characterized by polymorphism and atypical affective symptoms, which require careful differential diagnosis, considering disorders of other nosological categories and pathological pubertal crisis. Early recognition of type II bipolar affective disorder is associated with difficulties in hypomanic episode identification that are not regarded by patients as painful in most cases and are not a reason for seeking psychiatric advice and care.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассмотрен клинический случай биполярного аффективного расстройства II типа. Обсуждаются трудности диагностики на ранних этапах заболевания. Клинический пример отражает картину из реальной психиатрической практики, когда дебют заболевания отмечается в подростковом возрасте и связан с воздействием психотравмирующей ситуации. Манифестация заболевания отличается полиморфизмом и атипичностью аффективных симптомов, что требует тщательной дифференциальной диагностики с расстройствами других нозологических категорий и патологическим пубертатным кризом. Раннее распознавание биполярного аффективного расстройства II типа также связано с трудностями выявления гипоманиакальных эпизодов, которые в большинстве случаев не расцениваются пациентами как болезненные и не служат поводом для обращения за психиатрической помощью.</p></trans-abstract><kwd-group xml:lang="en"><kwd>bipolar affective disorder type II</kwd><kwd>hypomania</kwd><kwd>puberty crisis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>биполярное аффективное расстройство II типа</kwd><kwd>гипомания</kwd><kwd>пубертатный криз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Psikhicheskie i povedencheskie rasstroĭstva. Klinicheskie opisaniya i ukazaniya po diagnostike [Internet]. ICD-10 [cited 2022 Jul 10]. Available from: https://psychiatr.ru/news/181. (In Russ).</mixed-citation><mixed-citation xml:lang="ru">Психические и поведенческие расстройства. 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