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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Russian Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-2106</issn><issn publication-format="electronic">2412-9100</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">38082</article-id><article-id pub-id-type="doi">10.17816/rmj38082</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE CROSS-LINKING OF CORNEAL COLLAGEN IN TREATMENT OF TROPHIC AND BACTERIAL ULCERS OF CORNEA</article-title><trans-title-group xml:lang="ru"><trans-title>КРОСС-ЛИНКИНГ РОГОВИЧНОГО КОЛЛАГЕНА В ЛЕЧЕНИИ ТРОФИЧЕСКИХ И БАКТЕРИАЛЬНЫХ ЯЗВ РОГОВИЦЫ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Neroyev</surname><given-names>V. V</given-names></name><name xml:lang="ru"><surname>Нероев</surname><given-names>В. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Petukhova</surname><given-names>A. B</given-names></name><name xml:lang="ru"><surname>Петухова</surname><given-names>Анастасия Борисовна</given-names></name></name-alternatives><email>Petuhova-a-b@mailr</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Danilova</surname><given-names>D. Yu</given-names></name><name xml:lang="ru"><surname>Данилова</surname><given-names>Д. Ю</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Seliverstova</surname><given-names>K. E</given-names></name><name xml:lang="ru"><surname>Селиверстова</surname><given-names>К. Е</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gundorova</surname><given-names>R. A</given-names></name><name xml:lang="ru"><surname>Гундорова</surname><given-names>Р. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The Helmholtz Moscow research institute of eye diseases of Minzdrav of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ Московский НИИ глазных болезней им. Гельмгольца Минздравсоцразвития России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2013</year></pub-date><volume>19</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2013)</issue-title><issue-title xml:lang="ru">№2 (2013)</issue-title><fpage>25</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Эко-Вектор"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://medjrf.com/0869-2106/article/view/38082">https://medjrf.com/0869-2106/article/view/38082</self-uri><abstract xml:lang="en"><p>The bacterial and trophic ulcers of cornea are an actual problem of modern ophthalmology. The severe outcomes in the form of persistent corneal caligo, length of courses of therapeutic treatment without persevering remission, development of such severe complications as perforation substantiate the search of new methods of treatment of the mentioned pathology.</p></abstract><trans-abstract xml:lang="ru"><p>Бактериальные и трофические язвы роговицы являются актуальной проблемой современной офтальмологии. Тяжелые исходы в виде стойких помутнений роговицы, длительность курсов терапевтического лечения, не приводящих к стойкой ремиссии, а также развитие таких тяжелых осложнений, как перфорация, обосновывают поиск новых методов лечения данной патологии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cross-linking</kwd><kwd>ulcer of cornea</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>кросс-линкинг</kwd><kwd>язва роговицы</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Вэндер Д.Ф., Голт Д.А. 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