<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Russian Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-2106</issn><issn publication-format="electronic">2412-9100</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">48515</article-id><article-id pub-id-type="doi">10.17816/0869-2106-2020-26-3-165-172</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical medicine</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клиническая медицина</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intellectual and mnestic disorders in children with spastic forms of infantile cerebral palsy depending on the level of gross motor functions</article-title><trans-title-group xml:lang="ru"><trans-title>Интеллектуально-мнестические нарушения у детей со спастическими формами детского церебрального паралича в зависимости от уровня глобальных моторных Функций</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0281-3262</contrib-id><name-alternatives><name xml:lang="en"><surname>Dzhomardly</surname><given-names>Elnur I.</given-names></name><name xml:lang="ru"><surname>Джомардлы</surname><given-names>Эльнур Исфандиярович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>mamedov.ie@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7843-3004</contrib-id><name-alternatives><name xml:lang="en"><surname>Lorer</surname><given-names>Viktoriya V.</given-names></name><name xml:lang="ru"><surname>Лорер</surname><given-names>Виктория Валерьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к. п. н.</p></bio><email>lorer@list.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0862-8826</contrib-id><name-alternatives><name xml:lang="en"><surname>Koltsov</surname><given-names>Andrey A.</given-names></name><name xml:lang="ru"><surname>Кольцов</surname><given-names>Андрей Анатольевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к. м. н.</p></bio><email>katandr2007@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2038-6476</contrib-id><name-alternatives><name xml:lang="en"><surname>Zolotareva</surname><given-names>Anastasia A.</given-names></name><name xml:lang="ru"><surname>Золотарева</surname><given-names>Анастасия Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Anazol_97@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">G.A. Albrecht Federal scientific center of rehabilitation disabled people</institution></aff><aff><institution xml:lang="ru">ФГБУ «Федеральный научный центр реабилитации инвалидов им. Г. А. Альбрехта» Министерства труда и социальной защиты Российской Федерации</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">I.P. Pavlov First Pavlov State Medical University of St. Petersburg</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2020</year></pub-date><volume>26</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>165</fpage><lpage>172</lpage><history><date date-type="received" iso-8601-date="2020-10-24"><day>24</day><month>10</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-10-24"><day>24</day><month>10</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Эко-Вектор"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2023-10-24"/></permissions><self-uri xlink:href="https://medjrf.com/0869-2106/article/view/48515">https://medjrf.com/0869-2106/article/view/48515</self-uri><abstract xml:lang="en"><p>Background. The clinical manifestations of infantile cerebral palsy (ICP) are caused by both basic neurological and other comorbid conditions, such as secondary orthopedic and statodynamic disorders, hearing and speech disorders, nutritional disorders, epilepsy and, often, intellectual and mnestic disorders. Accordingly, the approach to treatment and rehabilitation of such patients should be interdisciplinary. To improve the quality of communication between different specialists, the International Classification of Functioning, Disability, and Health (ICF) has been developed and is actively being introduced into clinical practice.</p> <p>The study aimed to investigate the intellectual and mnestic functions in children with spastic forms of ICP depending on the gross motor function level.</p> <p>Material and methods. A prospective examination of 73 pediatric patients with spastic forms of ICP, aged 4 to 17 years, included by random sampling, was performed. The patients were divided into five groups based on the classification of the Gross Motor Function Classification System (GMFCS). The study methodological basis is ICF basic provisions. To assess the intellectual and mnestic functions, six categories were used, which are included in the ICF section “Mental functions.”</p> <p>Results. A correlation between the intellectual and mnestic disorders and the GMFCS level was revealed. Multiple pairwise intergroup comparisons showed statistically significant differences (p &lt; 0.05) for all categories under study between Groups GMFCS 1 and GMFCS 5, GMFCS 2 and GMFCS 5, and GMFCS 3 and GMFCS 5, although the difference between Groups GMFCS 4 and GMFCS 5 was identified in only three categories.</p> <p>Conclusion. The severity of disorders of the intellectual and mnestic functions in ICP pediatric patients varies widely depending on the level of gross motor functions. A correlation was revealed between the main intellectual and mnestic function indicators and the GMFCS level. Assessment of intellectual and mnestic functions due to its variability in pediatric patients with different levels of GMFCS when choosing the optimal treatment approach is appropriate.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность. Клинические проявления детского церебрального паралича (ДЦП) обусловлены как основным неврологическим, так и другими коморбидными состояниями, такими, как вторичные ортопедические и статодинамические нарушения, нарушения слуха и речи, нутритивные нарушения, эпилепсия и, нередко, интеллектуально-мнестические нарушения. Соответственно, подход к лечению и реабилитации таких больных – междисциплинарный. С целью повышения качества коммуникации между разными специалистами разработана и активно внедряется в клиническую практику Международная классификация функционирования, ограничений жизнедеятельности и здоровья (МКФ). Цель. Исследовать интеллектуально-мнестические функции у детей со спастическими формами ДЦП в зависимости от уровня глобальных моторных функций. Материал и методы. Выполнено проспективное обследование 73 детей со спастическими формами ДЦП в возрасте от 4 до 17 лет включительно, сформированное методом случайной выборки. Пациенты разделены на 5 групп в соответствии с классификацией глобальных моторных функций (GMFCS). Методологической основой исследования являются базовые положения МКФ. Для оценки интеллектуально-мнестических функций использованы 6 категорий, входящие в раздел МКФ «Умственные функции». Результаты. Выявлена корреляционная связь между интеллектуально-мнестическими нарушениями и уровнем GMFCS. Множественное попарное межгрупповое сравнение показало статистически значимые различия (p &lt; 0,05), по всем исследуемым категориям, между группами GMFCS 1 и GMFCS 5, GMFCS 2 и GMFCS 5, GMFCS 3 и GMFCS 5. Тогда как различие между группами GMFCS 4 и GMFCS 5 выявлено лишь по трём категориям.</p> <p>Выводы. Выраженность нарушений интеллектуально-мнестических функций у детей с ДЦП варьирует в широких пределах в зависимости от уровня глобальных моторных функций; выявлена корреляционная связь между основными показателями интеллектуально-мнестических функций и уровнем GMFCS; оценка интеллектуально-мнестических функций ввиду ее вариабельности у детей с различными уровня GMFCS при выборе оптимальной тактики лечения является целесообразной.</p></trans-abstract><kwd-group xml:lang="en"><kwd>infantile cerebral palsy</kwd><kwd>ICF</kwd><kwd>intelligence</kwd><kwd>attention</kwd><kwd>memory</kwd><kwd>GMFCS</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>детский церебральный паралич</kwd><kwd>МКФ</kwd><kwd>интеллект</kwd><kwd>внимание</kwd><kwd>память</kwd><kwd>GMFCS</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Valentina J., Davidson S.A., Bear N., Blair E., Paterson L., Ward R. et al. A prospective study investigating gross motor function of children with cerebral palsy and GMFCS level II after long-term botulinum toxin type A use. BMC Pediatrics. 2020;20(1):7. Doi: 10.1186/s12887-019-1906-8.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Collado-Garrido L., Paras-Bravo P., Calvo-Martin P., Santibanez-Marguello M. Impact of resistance therapy on motor function in children with cerebral palsy: A systematic review and meta-analysis. Int J Environ Res Public Health. 2019;16(22):e4513. Doi: 10.3390/ijerph16224513.</mixed-citation></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Horber V., Fares A., Platt M.J., Arnaud C., Krageloh-Mann I., Sellier E. Severity of cerebral palsy – the impact of associated impairments. Neuropediatrics. 2020;51(2):120-8. Doi: 10.1055/s-0040-1701669.</mixed-citation><mixed-citation xml:lang="ru">Horber V., Fares A., Platt M.J., Arnaud C., Krageloh-Mann I., Sellier E. Severity of cerebral palsy – the impact of associated im¬pair-ments. Neuropediatrics. 2020;51(2):120-8. Doi: 10.1055/s-0040-1701669.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><mixed-citation>Pruitt D.W., Tsai T. Common medical comorbidities associated with cerebral palsy. Phys Med Rehabil Clin N Am. 2009;20(3):453-67. Doi: 10.1016/j.pmr.2009.06.002.</mixed-citation></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Venkateswaran S., Shevell M. Comorbidities and clinical determinants of outcome in children with spastic quadriplegic cerebral palsy. Dev Med Child Neurol. 2008;50(3):216-22. Doi: 10.1111/j.1469-8749.2008.02033.x.</mixed-citation><mixed-citation xml:lang="ru">Venkateswaran S., Shevell M. Comorbidities and clinical deter¬minants of outcome in children with spastic quadriplegic cere¬bral palsy. Dev Med Child Neurol. 2008;50(3):216-22. Doi: 10.1111/j.1469-8749.2008.02033.x.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><mixed-citation>Palisano R., Rosenbaum P., Walter S., Russell D., Wood E., Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997;39(4):214-23. Doi: 10.1111/j.1469-8749.1997.tb07414.x.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Choi J.Y., Park J., Choi Y.S., Goh Y.R., Park E.S. Functional communication profiles in children with cerebral palsy in relation to gross motor function and manual and intellectual ability. Yonsei Med J. 2018;59(5):677-85. Doi: 10.3349/ymj.2018.59.5.677.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Kwon K.B., Choi Y., Sung K.H., Chung C.Y., Lee S.S., Cho G.H. et al. Correlation between accelerometer and questionnaire-based assessment of physical activity in patients with cerebral palsy. Clin Orthop Surg. 2020;12(1):107-22. Doi: 10.4055/cios.2020.12.1.107.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Patel D.R., Neelakantan M., Pandher K., Merrick J. Cerebral palsy in children: a clinical overview. Transl Pediatr. 2020;9(Suppl. 1):S125-35. Doi: 10.21037/tp.2020.01.01.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Schwemmle C., Arens C. Feeding, eating, and swallowing disorders in infants and children: an overview. HNO. 2018;66(7):515-26. Doi: 10.1007/s00106-017-0388-y.</mixed-citation></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Lorer V.V., Zhukova T.N. Application of the International Classification of Functioning, Disability and Health in assessment of integra¬ted rehabilitation of disabled people. Klinicheskaya i spetsial’naya psikhologiya 2017;6(3):116-34. (In Russ.) Doi: 10.17759/cpse. 2017060307.</mixed-citation><mixed-citation xml:lang="ru">Лорер В.В., Жукова Т.Н. Применение Международной классификации функционирования, ограничений жизнедеятельности и здоровья в оценке комплексной реабилитации инвалидов. Клиническая и специальная психология. 2017;6(3):116-34. Doi: 10.17759/cpse.2017060307.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><mixed-citation>International classification of impairments, disability and health. Geneva: WHO; 2001. 342 p.</mixed-citation></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Shabalov N.P. Pediatrics: Textbook. [Pediatriya: Uchebnik]. St. Petersburg: SpetsLit; 2003:31-2. (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Шабалов Н.П. Педиатрия: Учебник. СПб.: СпецЛит; 2003: 31-2.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Glozman Zh.M., Potanina A.Yu., Soboleva A.E. Neuropsychological diagnosis at preschool age. [Neiropsikhologicheskaya diagnostika v doshkol’nom vozraste]. 2nd ed. St. Petersburg: Piter; 2008. 80 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Глозман Ж.М., Потанина А.Ю., Соболева А.Е. Нейропсихологическая диагностика в дошкольном возрасте. 2-е изд. СПб.: Питер: 2008. 80 с.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Semenovich A.V. Neiropsikhologicheskaya diagnostika i korrektsiya v detskom vozraste: Uchebnoe posobie dlya vysshikh uchebnykh zavedenii. [Neuropsychological Diagnosis and Correction in Childhood: Textbook]. Moscow: Akademiya; 2002. 232 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Семенович А.В. Нейропсихологическая диагностика и коррекция в детском возрасте: Учебное пособие для высших учебных заведений. М.: Академия; 2002. 232 с.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Postnikova A.A. Features of the development of verbal and logical thinking in children of primary school age with cerebral palsy. Sovremennye innovatsii. 2018;(1):76-8. (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Постникова А.А. Особенности развития словесно-логического мышления у детей младшего школьного возраста с детским церебральным параличом. Современные инновации. 2018;(1): 76-8.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><mixed-citation>Stadskleiv K. Cognitive functioning in children with cerebral palsy. Dev Med Child Neurol. 2020;62(3):283-9. Doi: 10.1111/dmcn.14463.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Dalvand H., Dehghan L., Hadian M.R., Feizy A., Hosseini S.A. Relationship between gross motor and intellectual function in children with cerebral palsy: a cross-sectional study. Arch Phus Med Rehabil. 2012;93(3):480-4. Doi: 10.1016/j.apmr.2011.10.019.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Choi J.Y., Park J., Choi Y.S., Goh Y.R., Park E.S. Functional communication profiles in children with cerebral palsy in relation to gross motor function and manual and intellectual ability. Yonsei Med J. 2018;59(5):677-85. Doi: 10.3349/ymj.2018.59.5.677.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Fluss J., Lidzba K. Cognitive and academic profiles in children with cerebral palsy: a narrative review. Ann Phys Rehabil Med. 2020; S1877-0657(20)30036-1. Doi: 10.1016/j.rehab.2020.01.005.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Minciu I. Clinical correlations in cerebral palsy. Maedica (Buchar). 2012;7(4):319-24.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Christine C., Dolk H., Platt M.J., Colver A., Prasauskiene A., Krägeloh-Mann I. Recommendations from the SCPE collaborative group for defining and classifying cerebral palsy. Dev Med Child Neurol. 2007;49:35-8. Doi: 10.1111/j.1469-8749.2007.tb12626.x.</mixed-citation></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">N’okikt’en Ch. Pediatric Behavioral Neurology. [Detskaya povedencheskaya nevrologiya]. Ed by N.N. Zavadenko. 3rd ed. Moscow: Terevinf; 2018. 288 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Ньокиктьен Ч. Детская поведенческая неврология / Под ред. Н.Н. Заваденко. 3-е изд. М.: Теревинф; 2018. 288 с.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><mixed-citation>Chokron S., Dutton G.N. Impact of cerebral visual impairments on motor skills: implication for developmental coordination disorders. Front Psychol. 2016;7:1471. Doi: 10.3389/fpsyg.2016.01471.</mixed-citation></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">Ego A., Lidzba K., Brovedani P., Belmonti V., Gonzalez-Monge S., Boudia B. et al. Visual-perceptual impairment in children with cerebral palsy: a systematic review. Dev Med Child Neurol. 2015;57: 46-51. Doi: 10.1111/dmcn.12687.</mixed-citation><mixed-citation xml:lang="ru">Ego A., Lidzba K., Brovedani P., Belmonti V., Gonzalez-Monge S., Boudia B. et al. Visual-perceptual impairment in children with cerebral palsy: a systematic review. Dev Med Child Neurol. 2015; 57:46-51. Doi: 10.1111/dmcn.12687.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><mixed-citation>Pavão S.L., Rocha N.A. Sensory processing disorders in children with cerebral palsy. Infant Behav Dev. 2017;46:1-6. Doi: 10.1016/j.infbeh.2016.10.007.</mixed-citation></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">Nemkova S.A. Mental impairment in children with cerebral palsy: diagnosis and treatment. Zhurnal nevrologii i psikhiatrii im. C.C. Kor-sakova. 2018;118(2):105-13. (In Russ.) Doi: 10.17116/jnevro201811821105-113.</mixed-citation><mixed-citation xml:lang="ru">Немкова С.А. Нарушения психического развития при детском церебральном параличе: комплексная диагностика и коррекция. Журнал неврологии и психиатрии им. C.C. Корсакова. 2018; 118(2):105-13. Doi: 10.17116/jnevro201811821105-113.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">Vysotskaya E.P. Features of the development of mental functions of children with cerebral palsy. Gumanitarnye nauchnye issledovaniya. 2019;(2):1. Available at: http://human.snauka.ru/2019/02/25629 (accessed 27 March 2019). (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Высоцкая Е.П. Особенности развития психических функций детей с церебральным параличом. Гуманитарные научные исследования. 2019;(2):1. Available at: http://human.snauka.ru/2019/02/25629 (дата обращения 27.03.2019).</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><mixed-citation>Kaufman J., Warschausky S. Visuo-spatial and auditory working memory in children with cerebral palsy. Arch Phys Med Rehabil. 2015;96(10):e86–7. Doi: 10.1016/j.apmr.2015.08.289.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Hou M., Sun D.R., Shan R.B., Wang K., Yu R., Zhao J.H., Jiang Y.P. Comorbidities in patients with cerebral palsy and their relationship with neurologic subtypes and Gross Motor Function Classification System levels. Zhonghua Er Ke Za Zhi. 2010;48(5):351-4.</mixed-citation></ref></ref-list></back></article>
