Russian MedicineRussian MedicineРоссийский медицинский журнал0869-21062412-9100Eco-Vector4851810.17816/0869-2106-2020-26-3-179-187ReviewsНаучные обзорыReview ArticleCOVID-19: from neurotropism to neurorehabilitation under a pandemic conditionCOVID-19: от нейротропизма к нейрореабилитации в условиях пандемииhttps://orcid.org/0000-0001-7684-9834MerkulovYury A.МеркуловЮрий Александрович
Russian Federation

MD, PhD, DSc

д.м.н.

4181220@gmail.comhttps://orcid.org/0000-0003-0629-9659KostenkoElena V.КостенкоЕлена Владимировна
Russian Federation

MD, PhD, DSC, Professor

д.м.н., профессор

Ekostenko58@mail.ruhttps://orcid.org/0000-0003-0368-683XMerkulovaDina M.МеркуловаДина Мироновна
Russian Federation

MD, PhD, DSc, Professor

д.м.н., профессор

dinamerk@mail.ruhttps://orcid.org/0000-0001-6939-3234LyaminaNadezhda P.ЛяминаНадежда Павловна
Russian Federation

MD, PhD, DSc, Professor

д.м.н., профессор

lyana_n@mail.ruMoscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports MedicineГАУЗ «Московский научно-практический центр медицинской реабилитации, восстановительной и спортивной медицины ДЗМ»Scientific Research Institute of General Pathology and PathophysiologyФГБНУ «НИИ общей патологии и патофизиологии»N.I. Pirogov Russian National Research Medical UniversityФГАОУ ВО «РНИМУ им. Н.И. Пирогова» Минздрава РоссииI.M. Sechenov First Moscow State Medical University (Sechenov University)ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова (Сеченовский Университет)» Минздрава России151020202631791872410202024102020Copyright ©; 2020, Eco-VectorCopyright ©; 2020, ООО "Эко-Вектор"2020Eco-VectorООО "Эко-Вектор"https://medjrf.com/0869-2106/article/view/48518

In the review presented, based on the relevant literature data from foreign experts, the mechanisms of the neurotrophic action of the SARS-CoV-2 virus are considered, as well as the consequences of its neuroinvasion in the form of documented neurological manifestations during the COVID-19 pandemic. The risks of neurological diseases and methods of their treatment are analyzed, which in turn can affect the susceptibility to COVID-19. The range of rehabilitation syndromes is systematized, and relevant aspects of medical rehabilitation of patients after COVID-19 with an emphasis on its neurological manifestations are highlighted.

В представленном обзоре на основании актуальных литературных данных зарубежных специалистов рассмотрены механизмы нейротропного действия вируса SARS-CoV-2 и последствия его нейроинвазии в виде задокументированных неврологических проявлений в период пандемии COVID-19. Приведен анализ рисков неврологических заболеваний и методов их лечения, которые в свою очередь могут воздействовать на восприимчивость к COVID-19. Систематизирован спектр реабилитационных синдромов и освещены актуальные аспекты медицинской реабилитации пациентов, перенесших COVID-19, с акцентом на его неврологические проявления.

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