The effect of vitamins and micronutrients on the intestinal microbiota in norm and pathology

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详细

It is known that the intestinal microbiome plays an important role in many biological processes of the human body. However, all factors and mechanisms influencing changes in the composition of the intestinal microbiome are not fully understood. As the results of previous studies show, long-term food preferences play a significant role in modulating the composition of the intestinal microbiota. At the same time, all the mechanisms fully reflecting the peculiarities of the relationship of vitamins, trace elements, and the composition of the intestinal microbiota are not adequately characterized.

Vitamins and trace elements have a bidirectional effect on the intestinal microbiota. On the one hand, they influence the composition of the microbiota, its representation, number, and diversity. On the other hand, the microbiota is involved in the metabolism of trace elements, including the synthesis of certain vitamins.

In this review, we have tried to summarize the currently known information reflecting the relationship between the main microelements and the bacterial community of the gut. The review showed that some vitamins, with additional use, entering the colon modulate its microbiome, increase and maintain the bacterial diversity of the gut microbiota, which affects the amount of synthesized short-chain fatty acids. Several vitamins, such as vitamins A and D, can also affect intestinal immunity and its barrier functions.

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作者简介

Alexandra Nekrasova

Centre for Strategic Planning and Management of Biomedical Health

编辑信件的主要联系方式.
Email: akinshina@cspfmba.ru
ORCID iD: 0000-0002-7951-2003
SPIN 代码: 8168-0163
俄罗斯联邦, Moscow

Irina Kalashnikova

Centre for Strategic Planning and Management of Biomedical Health

Email: igkalashnikova@cspfmba.ru
ORCID iD: 0009-0003-8764-3286
SPIN 代码: 4203-1495
俄罗斯联邦, Moscow

Ekaterina Petryaykina

Centre for Strategic Planning and Management of Biomedical Health

Email: EPetryakina@cspfmba.ru
ORCID iD: 0000-0001-6680-6515
SPIN 代码: 5353-9399
俄罗斯联邦, Moscow

Alexander Nekrasov

Centre for Strategic Planning and Management of Biomedical Health

Email: anekrasov@cspfmba.ru
ORCID iD: 0009-0001-2142-4166
SPIN 代码: 6198-7379
俄罗斯联邦, Moscow

Vladimir Yudin

Centre for Strategic Planning and Management of Biomedical Health

Email: vyudin@cspfmba.ru
ORCID iD: 0000-0002-9199-6258
SPIN 代码: 7592-9020

Cand. Sci. (Biology)

俄罗斯联邦, Moscow

Valentin Makarov

Centre for Strategic Planning and Management of Biomedical Health

Email: makarov@cspfmba.ru
ORCID iD: 0000-0001-9495-0266
SPIN 代码: 7842-8808

Cand. Sci. (Biology)

俄罗斯联邦, Moscow

Anton Keskinov

Centre for Strategic Planning and Management of Biomedical Health

Email: keskinov@cspfmba.ru
ORCID iD: 0000-0001-7378-983X
SPIN 代码: 7178-5020

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Moscow

Sergey Yudin

Centre for Strategic Planning and Management of Biomedical Health

Email: yudin@cspmz.ru
ORCID iD: 0000-0002-7942-8004
SPIN 代码: 9706-5936

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Moscow

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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