Etiology of enterococcal bacteria: literature review and own data

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Abstract

The relevance of the work is due to the worldwide increase in the number of hospital bloodstream infections associated with bacteria of the genus Enterococcus spp. The ability to acquire and distribute antibiotic resistance determinants contributed to the transformation of enterococci from opportunistic pathogens to a significant problem in medical institutions.

This review aimed to analyze the materials published in 2015–2020 on epidemiological risk factors for enterococcal bacteremia and microbial enterococci resistance. The clinical difference between Enterococcus faecalis and Enterococcus faecium was discussed as well as the virulence factors and antibiotic tolerance of enterococci. The study presented own data on enterococcal bacteremia in the early period in vital organs in recipients.

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About the authors

Nina I. Gabrielyan

V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs

Email: labgso@mail.ru

MD, PhD, DSc

Russian Federation, 123182, Moscow

Viktoriya G. Kormilitsina

V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs

Email: v16k@rambler.ru
Russian Federation, 123182, Moscow

Irina V. Drabkina

V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs

Email: drabkina58@mail.ru
Russian Federation, 123182, Moscow

Rinat Sh. Saitgareev

V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs

Email: rinat.saitgareev@rambler.ru

MD, PhD, DSc, Professor

Russian Federation, 123182, Moscow

Vyacheslav M. Zakharevich

V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs; I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: zaharslava@yandex.ru

MD, PhD, DSc, Professor

Russian Federation, 123182, Moscow; 119991, Moscow

Olga V. Kisil

G.F. Gause Institute of New Antibiotics

Author for correspondence.
Email: olvv@mail.ru

PhD (Chem.)

Russian Federation, 119991, Moscow

Viktor V. Maleev

Central Research Institute of Epidemiology

Email: maleyev@pcr.ru

MD, PhD, DSc, Professor, academician of RAS

Russian Federation, 111123, Moscow

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