Biology BulletinBiology BulletinИзвестия Российской академии наук. Серия биологическая1026-34703034-5367The Russian Academy of Sciences64780410.31857/S1026347024030073VAROZBФИЗИОЛОГИЯ ЖИВОТНЫХ И ЧЕЛОВЕКАResearch ArticleThe blood leukocytes and platelets of little ground squirrels (Spermophilus pygmaeus Pall.) during hibernation and arousalЛейкоциты и тромбоциты крови малых сусликов (Spermophilus pygmaeus Pall.) при зимней спячке и пробужденииDzhafarovaA. M.ДжафароваА. М.
Russian Federation
klich-khan@mail.ruChalabovSh. I.ЧалабовШ. И.
Russian Federation
klich-khan@mail.ruKlichkhanovN. K.КличхановН. К.
Russian Federation
klich-khan@mail.ruDagestan State UniversityДагестанский государственный университетI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of SciencesИнститут эволюционной физиологии и биохимии И. М. Сеченова РАН12102024335837428012025Copyright ©; 2024, Russian Academy of SciencesCopyright ©; 2024, Российская академия наук2024Russian Academy of SciencesРоссийская академия наукhttps://medjrf.com/1026-3470/article/view/647804

During hibernation, mammals periodically go through cold (torpor) and warm (awakening) phases. Previously, a sharp decrease in the levels of leukocytes and blood platelets in the torpid state was found, but the dynamics of their changes during arousal remains unknown. We have studied the content and composition of the circulating cells of the little ground squirrel during arousal. The number of all types of leukocytes and platelets in the torpid state is significantly reduced. Restoration of the level of leukocytes in the blood during arousal occurs in two phases: fast (Tb 10—20°C) and slow (Tb 20—37°C). Unlike other cell types, the content of neutrophils remains below euthermal condition after body temperature recovery. During arousal in the Tb range of 10—30°C, the level of platelets increases linearly, while the normalization of the P-LCR parameter does not occur.

В период гибернации млекопитающие периодически проходят холодную (торпор) и теплую (пробуждение) фазы. Ранее было обнаружено резкое снижение уровней лейкоцитов и тромбоцитов крови в торпидном состоянии, однако динамика их изменений во время пробуждения остается неизвестной. Нами изучены содержание и состав циркулирующих клеток малого суслика во время пробуждения. Количество всех типов лейкоцитов и тромбоцитов в торпидном состоянии существенно снижается. Восстановление уровня лейкоцитов в крови в ходе пробуждения происходит в две фазы: быстрая (Tb 10—20°C) и медленная (Tb 20—37°C). В отличие от других типов клеток содержание нейтрофилов после восстановления температуры остается ниже контроля. Во время пробуждения в диапазоне Tb 10—30°C линейно возрастает уровень тромбоцитов, при этом нормализации параметра P-LCR не происходит.

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