Biology BulletinBiology BulletinИзвестия Российской академии наук. Серия биологическая1026-34703034-5367The Russian Academy of Sciences67502910.31857/S1026347022700093HJSFZCDEVELOPMENTAL BIOLOGYБИОЛОГИЯ РАЗВИТИЯRole of Albumin and Alpha-Fetoprotein in Prenatal Ontogenesis of the Human EyeРоль альбумина и альфа-фетопротеина в пренатальном онтогенезе глаза человекаPanovaI. G.ПановаИ. Г.pinag@mail.ruTatikolovA. S.ТатиколовА. С.pinag@mail.ruInternational Scientific and Practical Center of Tissue ProliferationНП Международный научно-практический центр пролиферации тканейEmanuel Institute of Biochemical Physics, Russian Academy of SciencesИнститут биохимической физики им. Н.М. Эмануэля РАН01032023212213328022025Copyright ©; 2023, И.Г. Панова, А.С. ТатиколовCopyright ©; 2023, И.Г. Панова, А.С. Татиколов2023И.Г. Панова, А.С. ТатиколовИ.Г. Панова, А.С. Татиколовhttps://medjrf.com/1026-3470/article/view/675029

The vitreous body of the eye of human fetuses contains serum albumin (SA) and alpha-fetoprotein (AFP), which is normally characteristic of human embryos and fetuses. In the second trimester, both proteins are found in the vitreous at a concentration comparable to that in blood serum, after which their content decreases sharply. In this analytical review, taking into account the biological properties of SA and AFP, the role of these proteins in the processes of growth and differentiation of the structures of the developing eye is discussed.

В стекловидном теле глаза плодов человека присутствуют сывороточный альбумин (СА) и альфа-фетопротеин (АФП), который в норме характерен для эмбрионов и плодов человека. Во втором триместре оба белка находятся в стекловидном теле в концентрации, сравнимой с концентрацией в сыворотке крови, после чего их содержание резко снижается. В настоящем аналитическом обзоре с учетом биологических свойств СА и АФП обсуждается роль этих белков в процессах роста и дифференцировки структур развивающегося глаза.

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