The effect of fluoride and hydroxyapatite in the composition of toothpastes on the remineralization and acid resistance of enamel

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

Introduction. The use of toothpastes is the most common way for the prevention of caries. There is a variety of different toothpastes available on the market and the choice of the most efficient paste for the particular case is of great interest and importance.

Aims: the purpose of the study was to assess the impact of toothpastes containing hydroxyapatite and fluoride on resistance of enamel to demineralization and enamel remineralization rate.

Material and methods. One hundred sixty patients participated in the study. The test and control groups included 80 patients each: 40 - at the age of 15-17 and 40 at the age of 18-25 who have been using toothpastes with hydroxyapatite or fluoride during 1 year, respectively. The oral hygiene assessment was carried out with the use of Turesky index. The clinical determination of enamel remineralization rate, and enamel resistance to demineralization were assessed to evaluate the remineralizing potential of toothpastes containing hydroxyapatite or fluoride.

Results. There was a statistically significant increase in the values of enamel resistance to demineralization and remineralization rates in all groups comparing to the baseline after 1-3 months of the use of the toothpastes prescribed. It was found that enamel resistance to demineralization and remineralization rates of enamel in the test group were significantly higher (p<0.05) compared with the group of patients using the toothpaste with fluoride.

Conclusion. Use of toothpastes containing hydroxyapatite and fluoride in conjunction with constant control of oral hygiene significantly increased the enamel demineralization resistance and enamel remineralization rate. However, toothpastes with hydroxyapatite were significantly more efficient and exhibited its action earlier in time.

Авторлар туралы

Mariya Polyakova

I.M. Sechenov First Moscow State Medical University

Хат алмасуға жауапты Автор.
Email: mafka-03@mail.ru
ORCID iD: 0000-0002-4494-2644

PhD, assistant professor of the department of therapeutic dentistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation.

e-mail: mafka-03@mail.ru

Ресей

K. Babina

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0003-4445-0858
Ресей

I. Makeeva

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-7878-0452
Ресей

N. Prochorov

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-4510-2890
Ресей

N. Novozhilova

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-1073-7693
Ресей

V. Doroshina

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0001-9971-8298
Ресей

M. Arakelyan

I.M. Sechenov First Moscow State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0001-5077-5136
Ресей

Әдебиет тізімі

  1. Visscher C.M., Lobbezoo F., Schuller A.A. Dental status and oral health-related quality of life. A population-based study. J Oral Rehabil. 2014; 41(6): 416–22. https://doi.org/10.1111/joor.12167
  2. Vlasova N.N. Evaluation of the effectiveness of the toothpaste Colgate Sensitive Pro-Relief to reduce the dentin hypersensitivity in the dental office. Novoye v stomatologii. 2010; 4: 8–10.
  3. Onoriobe U., Rozier R.G., Cantrell J., King R.S. Effects of enamel fluorosis and dental caries on quality of life. J Dent Res. 2014; 93 (10): 972–9. https://doi.org/10.1177/0022034514548705
  4. Costa Sde M., Vasconcelos M., Abreu M.H. Impact of dental caries on quality of life among adults resident in greater Belo Horizonte, State of Minas Gerais, Brazil. Cien Saude Colet. 2013; 18 (7): 1971–80.
  5. Horst J.A., Tanzer J.M., Milgrom P.M. Fluorides and Other Preventive Strategies for Tooth Decay. Dent Clin North Am. 2018; 62(2): 207–34.
  6. Marinho V.C., Higgins J.P., Logan S., Sheiham A. Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. 2003; (4): CD002782.
  7. Rugg-Gunn A., Bánóczy J. Fluoride toothpastes and fluoride mouthrinses for home use. Acta Med Acad. 2013; 42(2): 168–78. https://doi.org/10.5644/ama2006-124.84
  8. Walsh T., Worthington H.V., Glenny A.M., Appelbe P., Marinho V.C., Shi X. Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents (Review). Cochrane Database Syst Rev. 2010; (1): CD007868.
  9. Vano M., Derchi G., Barone A., Covani U. Effectiveness of nano-hydroxyapatite toothpaste in reducing dentin hypersensitivity: a double-blind randomized controlled trial. Quintessence Int. 2014; 45 (8): 703–11. https://doi.org/10.3290/j.qi.a32240
  10. Najibfard K., Ramalingam K., Chedjieu I., Amaechi B.T. Remineralization of early caries by a nano hydroxyapatite dentifrice. J Clin Dent. 2011; 22: 139–43.
  11. Huang S., Gao S., Yu H. Remineralization potential of nano-hydroxyapatite on initial enamel lesions: an in vitro study. Caries Res. 2011; 45: 460–8.
  12. Roveri N., Battistella E., Bianchi C.L. et al. Surface enamel remineralization: bio- mimetic apatite nanocrystals and fluoride ions different effects. J Nanomater. 2009: 746383.
  13. Tschoppe P., Zandim D.L., Martus P., Kielbassa A.M. Enamel and dentine remin eralization by nano-hydroxyapatite toothpastes. J Dent. 2011; 39: 430–7. https://doi.org/10.1016/j.jdent.2011.03.008
  14. Okushko V.R., Pedorets A.P. Functional resistance of dental enamel and its nerve regulation. Patol Fiziol Eksp Ter. 1980; 2: 65–7. (in Russian)
  15. Leont’ev V.K., Chekmezova I.V., Shevyrnogov V.Z. Effect of remineralization therapy on enamel mineralization processes and permeability. Stomatologiia (Mosk). 1983; 62 (5): 7–10. (in Russian)
  16. Walsh T., Worthington H.V., Glenny A.M., Appelbe P., Marinho V.C., Shi X. Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents (Review). Cochrane Database Syst Rev. 2010; 1: CD007868.
  17. Fowler C.E., Gracia L., Edwards M.I., Rees G.D., Brown A. Fluoride penetration from toothpastes into incipient enamel erosive lesions investigated using dynamic secondary ion mass spectrometry. J Clin Dent. 2009; 20 (6): 186–91.
  18. Creeth J.E., Kelly S.A., Martinez-Mier E.A., Hara A.T., Bosma M.L., Butler A. et al. Dose-response effect of fluoride dentifrice on remineralisation and further demineralisation of erosive lesions: A randomised in situ clinical study. J Dent. 2015; 43(7): 823–31. https://doi.org/10.1016/j.jdent.2015.03.008
  19. Lombardini M., Ceci M., Colombo M., Bianchi S., Poggio C. Preventive effect of different toothpastes on enamel erosion: AFM and SEM studies. Scanning. 2014; 36 (4): 401–10. https://doi.org/10.1002/sca.21132

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

© Polyakova M.A., Babina K.S., Makeeva I.M., Prochorov N.I., Novozhilova N.E., Doroshina V.Y., Arakelyan M.G., 2019



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 37884 от 02.10.2009.