Clinical-laboratory investigation of reproductive health of women living in ecologically unfavorable regions of Kazakhstan

In the area under study, mainly saline and solonetsous territories. The situation negatively affects the offspring of the population living in the region Continuing the work on assessing the impact of climatic and anthropogenic factors of the Aral region on the reproductive health of the female population, we compared the reproductive health of women living in five settlements of the Kyzylorda region and two settlements in the Karaganda region. There were observed 686 women in the zone of environmental crisis, 720 women living in the zone of environmental disaster and 388 women living in the Karaganda region in areas bordering the Aral Sea region. The examination was carried out on the basis of an integrated clinical-functional and laboratory examination, taking into account regional and environmental ecological factors. In the Kyzylorda region, there is a delayed onset of menarche occurred in girls older than 16 years (39%), there is a tendency to rejuvenate the age of the onset of menopause. In the Karaganda region, late menarche occurs only in 12% of cases. A third of the examined women suffered from inflammatory diseases of female genital organs in both regions. Perinatal losses, cases of spontaneous interruption and/or undeveloped pregnancies in the anamnesis are repeated many times, in zones of the ecological catastrophe and the environmental crisis there are frequent as one in four women. However, in the Karaganda region, this value figure was almost 3 times less (14%).