Biological prophylaxis in the system of the management of occupational risk due to exposure of metal-containing nanoparticles

Larisa I. Privalova; Привалова Лариса Ивановна; B. A. Katsnelson; Кацнельсон Б. А.; I. A. Minigalieva; Минигалиева И. А.; M. P. Sutunkova; Сутункова М. П.; O. G. Makeev; Макеев О. Г.; I. E. Valamina; Валамина И. Е.; V. Ya. Shur; Шур В. Я.; S. V. Klinova; Клинова С. В.; S. N. Solovyeva; Соловьёва С. Н.

doi:10.47470/0016-9900-2017-96-12-1187-1191

Biological prophylaxis in the system of the management of occupational risk due to exposure of metal-containing nanoparticles

Authors: Privalova L.I.¹, Katsnelson B.A.¹, Minigalieva I.A.¹, Sutunkova M.P.¹, Makeev O.G.², Valamina I.E.², Shur V.Y.³, Klinova S.V.¹, Solovyeva S.N.¹
Affiliations:
1. Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers
2. The Central Research Laboratory of the Ural Medical University
3. Ural Federal University
Issue: Vol 96, No 12 (2017)
Pages: 1187-1191
Section: PREVENTIVE TOXICOLOGY AND HYGIENIC STANDARTIZATION
Published: 21.10.2020
URL: https://medjrf.com/0016-9900/article/view/640736
DOI: https://doi.org/10.47470/0016-9900-2017-96-12-1187-1191
ID: 640736

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Abstract

With taking into account the biological toxicity of metallic and metal oxide nanoparticles to be a well-established fact, the widespread use of nanotechnologies and the significant proportion of nanoscale particles in industrial aerosols released during many pyrometallurgical and electric welding processes determine the importance of searching for approaches to increase the organism’s resistance to them. Results of a number of experiments show the application of combinations of some bioactive agents composed in accordance with sound theoretical premises and used in innocuous doses to be potent of the significant attenuation of the integral and specific toxicity of metallic nanoparticles and even their genotoxicity. Further research followed by practical application of the results is a promising trend in the occupational risk management strategy.

Keywords

metallic nanoparticles, bioprotectors

About the authors

Larisa I. Privalova

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers

Author for correspondence.
Email: privalovali@yahoo.com
ORCID iD: 0000-0002-1442-6737

MD, PhD, DSci., Professor Head of Laboratory of Scientific Bases for Biological Prophylaxis, Department of the Toxicology and Biological Prophylaxis, the Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, 620014, Russian Federation.

e-mail: privalovali@yahoo.com

Russian Federation

References

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Katsnel’son B.A., Privalova L.I., Sutunkova M.P., Gurvich V.B., Minigalieva I.A., Loginova N.V., et al. Main results of toxicological experiments in vivo with some metal and metal oxides nanoparticles. Toksikologicheskiy vestnik. 2015; (3): 26-39. (in Russian)
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