Effect of post-COVID syndrome on the quality of life of patients with allergic rhinitis and eosinophilic phenotype of chronic polyposis rhinosinusitis

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Abstract

BACKGROUND. An urgent issue of modern medicine is the study of the quality of life of people with post-COVID syndrome. Particular emphasis is placed on patients with various forms of allergic rhinitis associated with comorbid conditions such as polyposis rhinosinusitis. These diseases are still common and tend to increase. In this context, the study of the effect of conservative methods of treatment of allergic rhinitis and polyposis rhinosinus on the quality of life of patients will improve the effectiveness of the therapy.

 AIMS: To assess the impact of post-COVID syndrome on the quality of life of patients with various forms of allergic rhinitis and eosinophilic phenotype of chronic polyposis rhinosinusitis and to determine the effectiveness of conservative therapy.

MATERIALS AND METHODS: In the period from May to December 2021, a study was conducted on the quality of life in the treatment of 62 patients against the background of post-covid syndrome, of which 32 patients suffered from polypous rhinosinusitis and 30 patients with allergic rhinitis. The disease of coronavirus infection was registered 2-3 months before the visit to the otorhinolaryngologist. The comparison groups included 65 people, including 33 patients with polypous rhinosinusitis and 32 with various forms of allergic rhinitis. The Russian version of the standard SF-36 questionnaire was used to collect anamnesis. A visual analogue scale was used to measure the intensity of rhinological symptoms. All patients were examined three times: before treatment, 1 and 3 months after the course of therapy.

RESULTS: A comparative analysis of the quality of life indicators of patients with various forms of allergic rhinitis and polyposis rhinosinusitis showed a direct dependence on the condition of patients after a coronavirus infection. 

CONCLUSIONS: The use of the assessment of quality of life indicators at the stages of treatment of patients with various forms of allergic rhinitis and polypous rhinosinusitis against the background of post-covid syndrome makes it possible to determine the effectiveness of conservative therapy and timely adjust the treatment.

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About the authors

Musos Yu. Korkmazov

South Ural State Medical University

Author for correspondence.
Email: Korkmazov74@gmail.com
ORCID iD: 0000-0002-8642-0166

MD, dr. sci. (med.), professor

Russian Federation, 64 Vorovskiy street, 454092 Chelyabinsk

Maria A. Lengina

South Ural State Medical University

Email: Danilenko1910@mail.ru

MD, cand. sci. (med.), associate professor

Russian Federation, 64 Vorovskiy street, 454092 Chelyabinsk

Arsen M. Korkmazov

South Ural State Medical University

Email: Korkmazov09@gmail.com

MD, cand. sci. (med.), associate professor

Russian Federation, 64 Vorovskiy street, 454092 Chelyabinsk

Anna Yu. Kravchenko

South Ural State Medical University

Email: Anna4665@mail.ru

otorhinolaryngologist

Russian Federation, 64 Vorovskiy street, 454092 Chelyabinsk

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Supplementary files

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2. Fig. 1. Quality of life measure of respondents of the 1st group according to the scales of the SF-36 questionnaire; * here and in fig. 2–6 — statistically significant differences from the corresponding indicators of the control group; the nonparametric Mann–Whitney criterion was used for calculations at the significance level р <0.05. Here and in fig. 2–4: ФФ — physical functioning; ФС — physical condition; ИБ — pain intensity; ОСЗ — general state of health; ЖА — vital activity; СФ — social functioning; РФЭС — role functioning and role functioning due to emotional state; ПЗ — mental health.

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3. Fig. 2. Quality of life measure of group 2 according to the SF-36 questionnaire.

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4. Fig. 3. Quality of life measure of group 3 according to the SF-36 questionnaire.

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5. Fig. 4. Quality of life measure of group 4 according to the SF-36 questionnaire.

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6. Fig. 5. Сoncentration-time pattern of the difficulty in nasal breathing in all groups according to Visual Analogue Scale, points.

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7. Fig. 6. Сoncentration-time pattern of the incidence of rhinorrhea in all groups with allergic rhinitis and polyposis rhinosinusitis according to Visual Analogue Scale, points.

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