Bile reflux after laparoscopic mini / one anastomosis gastric bypass: the problem and prevention
- Authors: Vinnik Y.S.1, Chaykin A.A.2, Chaykin D.A.2, Teplyakova O.1, Yureva M.Y.1, Boyakova N.V.1, Vlasenko D.S.1, Bakhshyan V.A.1
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Affiliations:
- Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
- Clinical hospital «RZD-Medicine» city Krasnoyarsk
- Section: Reviews
- Submitted: 18.03.2024
- Accepted: 12.05.2024
- Published: 15.05.2024
- URL: https://medjrf.com/0869-2106/article/view/629187
- DOI: https://doi.org/10.17816/medjrf629187
- ID: 629187
Cite item
Abstract
Laparoscopic mini-gastric bypass (LMGB) is currently one of the three most common bariatric surgical operations. One of the reasons for reoperations after LMGB is pathological bile reflux, which, in addition to a noticeable decrease in the quality of life of patients, poses a potential threat to the development of neoplastic processes in the stomach and esophagus. The purpose of the study was to systematize and analyze modern literature information on terminology, diagnosis and frequency of detection, pathophysiological significance and methods of preventing bile reflux after LMGB. An analysis of Russian and English full-text literature sources on the problem of bile reflux after LMGB in the bibliographic databases of the Russian Science Citation Index, PubMed, Google Scholar, ScienceDirect was performed. The frequency of diagnosing bile reflux after LMGB varies from 2 to 57.9% depending on the instrumental diagnostic methods used: flexible endoscopy, 24-hour pH impedance measurements, spectrophotometry of bilirubin in refluxate, hepatobiliary scintigraphy. The pathogenetic effect of the contents of the small intestine on the mucous membrane of the stomach and esophagus after LMGB is mainly realized due to the direct cytotoxic and receptor-mediated effects of bile acids. The safety of the main stages of LMGB (creation of a gastric pouch and formation of a single anastomosis) is currently being reviewed from the standpoint of minimizing the risk of developing bile reflux. In addition, new techniques have been proposed to reduce the likelihood of intestinal contents entering the stomach and esophagus, but their effectiveness remains controversial.
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About the authors
Yurii S. Vinnik
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: yuvinnik@ya.ru
ORCID iD: 0000-0002-8995-2862
SPIN-code: 5070-8140
Russian Federation
Aleksandr A. Chaykin
Clinical hospital «RZD-Medicine» city Krasnoyarsk
Email: chaiki@inbox.ru
ORCID iD: 0009-0009-0994-081X
Dmitriy A. Chaykin
Clinical hospital «RZD-Medicine» city Krasnoyarsk
Email: conte4@yandex.ru
ORCID iD: 0000-0003-0098-1761
SPIN-code: 4098-5263
Olga Teplyakova
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Author for correspondence.
Email: teplyakova-olga@ya.ru
ORCID iD: 0000-0003-0005-3316
SPIN-code: 4975-0569
Scopus Author ID: 57627507000
ResearcherId: M-7060-2014
Professor, Professor, General Surgery Department named after Professor M. I. Gulman
Russian FederationMargarita Yu. Yureva
Email: hizhnenko2009@ya.ru
ORCID iD: 0009-0005-9185-278X
SPIN-code: 4551-1020
Nina V. Boyakova
Email: n79039248058@gmail.com
ORCID iD: 0000-0002-1761-4717
Dmitrii S. Vlasenko
Email: vdima2002@ya.ru
ORCID iD: 0009-0008-8550-5361
Valentina A. Bakhshyan
Email: v.a.bahshyan@gmail.com
ORCID iD: 0009-0000-5454-9961
SPIN-code: 6989-5951
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Supplementary files
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