Clinical significance of flash monitoring indicators in children with type 1 diabetes mellitus

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Abstract

A basic principle of the treatment of type 1 diabetes mellitus, along with insulin therapy and diet therapy, is regular self-monitoring of glycemia. Glucose meters are often used for daily self-monitoring, and devices for continuous and flash monitoring of glycemia have been used in recent years.

This review discusses the clinical aspects of the application of a glycemic monitoring system with periodic scanning (flash monitoring). The principle of operating the system and the main parameters obtained when using this system are described: time in the target range, time above and below the target range and their sub-ranges, indicators of glycemic variability and glycemic control, their normative levels, and their practical significance and relationship with the clinical aspects of the course of diabetes mellitus and prognosis of chronic complications.

The results of major international and domestic studies on the effectiveness of the flash monitoring system in different age groups are presented. The advantages of the second generation of flash glycemia monitoring sensors and results of clinical studies of the accuracy of this monitoring system in children and adult patients with diabetes mellitus are presented.

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About the authors

Irina L. Alimova

Smolensk State Medical University

Email: iri-alimova@yandex.ru
ORCID iD: 0000-0003-3230-1337
SPIN-code: 4583-9822

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Smolensk

Alexandra N. Demyanenko

Smolensk State Medical University

Author for correspondence.
Email: alex-glam@mail.ru
ORCID iD: 0000-0002-8787-6819
SPIN-code: 6889-8349

MD, Cand. Sci. (Medicine), Associate Professor

Russian Federation, Smolensk

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2. Fig. 1. Ambulatory glucose profile in patient K., born in 2009, with a diagnosis of type 1 diabetes mellitus. Green indicates time in the target range (91%), red indicates time below the target range (1%), yellow indicates time above the target range (8%). The duration of wearing the sensor (14 days), the time of sensor activity (88%), the glucose level control indicator (6.3%) and the coefficient of glycemic variability (26.1%) are indicated. All indicators are in target values

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