FACIAL NERVE NEUROPATHY DURING THE COVID-19 PANDEMIC: CLINICAL FEATURES, ACUPUNCTURE TREATMENT APPROACHES
- Authors: Andreeva G.O1, Odinak M.M2, Litvinenko E.V2, Lobzin V.Y.2, SHishkina E.V3
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Affiliations:
- S.M Kirov Military Medical Academy, Saint Petersburg, Russia
- Военно-медицинская академия имени С.М.Кирова
- Gorodskoj konsul'tativno-diagnosticheskij centr №1
- Section: Original Research Articles
- Submitted: 28.03.2024
- Accepted: 12.05.2024
- Published: 16.05.2024
- URL: https://medjrf.com/0869-2106/article/view/629544
- DOI: https://doi.org/10.17816/medjrf629544
- ID: 629544
Cite item
Abstract
The purpose of the study is to study the clinical features of the course of NLN after COVID-19. Develop reflexology approaches to treatment. To compare the course of NLN in patients with a history of coronavirus infection and without a history of COVID-19 infection.
Materials and methods. The study group (after COVID-19) consisted of 16 patients with neuropathy of the facial nerve (13 men, 3 women). The comparison group included 21 patients with NLN without a history of COVID-19 (men – 15; women – 6). For a comprehensive assessment of patients, data from clinical, neurological, and electroneuromyographic (ENMG) examinations were used.
Results. The results of treatment of 16 patients with neuropathy of the facial nerve developed up to 12 weeks after suffering from COVID-19 were analyzed. The onset of the disease was accompanied by an episode of arterial hypertension, which was observed for the first time in two patients. The damage to nerve fibers was mixed and severe (more than 52%). The dynamics of clinical and electrophysiological parameters in the study group (after COVID-19) were significantly slower compared to the group without a history of COVID.
Conclusion. Facial nerve neuropathy that develops after COVID-19 is characterized by severe damage to nerve fibers and a long course. Reflexology is an effective, safe method as part of complex therapy.
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About the authors
Galina O Andreeva
S.M Kirov Military Medical Academy, Saint Petersburg, Russia
Author for correspondence.
Email: galinandreev@yandex.ru
ORCID iD: 0000-0002-0350-3063
SPIN-code: 7128-6905
ResearcherId: I-4820-2016
M.D., D.Sc.
Russian Federation, 6, Akademika Lebedeva str., Saint Petersburg, 194044, RussiaMiroslav M Odinak
Военно-медицинская академия имени С.М.Кирова
Email: odinak@rambler.ru
ORCID iD: 0000-0002-7314-7711
SPIN-code: 1155-9732
Scopus Author ID: 7003327776
ResearcherId: I-6024-2016
Corresponding Member of the Russian Academy of Sciences, M.D., D.Sc. (Medicine), Professor
Russian Federation, 194044, Россия, Санкт-Петербург, ул. Академика Лебедева, д. 6Elena V Litvinenko
Военно-медицинская академия имени С.М.Кирова
Email: elenalitv@list.ru
ORCID iD: 0000-0002-2907-3129
SPIN-code: 5900-4225
заведующий кабинетом рефлексотерапии клиники нервных болезней
Russian Federation, 194044, Россия, Санкт-Петербург, ул. Академика Лебедева, д. 6Vladimir Yu Lobzin
Военно-медицинская академия имени С.М.Кирова
Email: vladimirlobzin@mail.ru
ORCID iD: 0000-0003-3109-8795
SPIN-code: 7779-3569
Scopus Author ID: 579578
ResearcherId: I-4819-2016
Professor
Russian Federation, 194044, Россия, Санкт-Петербург, ул. Академика Лебедева, д. 6El'vira V SHishkina
Gorodskoj konsul'tativno-diagnosticheskij centr №1
Email: elllia@mail.ru
acupuncturist doctor
Russian Federation, 10 Sikeyrosa str., Saint Petersburg, 194044 RussiaReferences
- Zammit M, Markey A, Webb C. A rise in facial nerve palsies during the coronavirus disease 2019 pandemic. J Laryngol Otol Suppl. 2020;134:905–908. doi: 10.1017/S0022215120002121.
- Odinak MM, Litvinenko IV, editors. Nervous diseases: a textbook for medical students. Saint Petersburg: SpecLit; 2020. (In Russ).
- Finsterer J, Scorza FA, Scorza C. et al. COVID-19 associated cranial nerve neuropathy: asystematic review. Bosn J Basic Med Sci. 2021; 21(1): 39-45. doi: 10.17305/bjbms.2021.6341.
- Islamoglu Y, Celik B, Kiris M. Facial paralys is as the only symptom of COVID-19: aprospectivestudy. Am J Otolaryngol. 2021;42:(4)102956. doi: 10.1016/j.amjoto.2021.102956
- Wu Y, Xu X, Chen Z, et al. Nervous system involvement a fterinfection with COVID-19 and other corona viruses. Brain Behav Immun. 2020;87:18–22. https://doi.org/10.1016/j.bbi.2020.03.031
- Belopasov VV, Yashu Y, Samoilova EM, et al. Damage to the nervous system due to COVID-19. Clinicheskaya practika. 2020;11(2):60–80. (In Russ). doi: 10.17816/clinpract34851.
- Litvinenko IV, Lobzin VY, Pushkarev VA, et al. Infectious hypothesis of neurodegenerative diseases. What can await us after the COVID-19 pandemic? Russian neurological journal. 2022;27(3):64-73. (In Russ). doi: 10.30629/2658-7947-2022-27-3-64-73.
- Vlasova TI, Spirina MA, Arsentieva EV, et al. Pathogenetic mechanisms of neurological post-Covid syndrome and the basis of its pathogenetic treatment and prevention (literature review). News of higher educational institutions. Volga region. Medical Sciences. 2021; 4:129–142. (In Russ). doi: 10.21685/2072-3032-2021-4-11
- Zhang R, Wu T, Wang R, et al. Compare the efficacy of acupuncture with drugs in the treatment of Bell's palsy: A systematic review and meta-analysis of RCTs. Medicine (Baltimore). 2019;98(19). doi: 10.1097/MD.0000000000015566.
- House JW, Brackmann DE. Facial nerve grading system. Am J Otolaryngol head neck surg. 1985; 93(2):146-147.
- Junkerov VI, Grigoriev SG, Rezvantsev MV. Mathematical and statistical processing of medical research data. Saint Petersburg: VMedA; 2011. (In Russ).
- National Institute for Health and Care Excellence. COVID-19 rapid guideline: managing the long-term effects of COVID-19. [Internet] [updated 2024 March 10]. Available from: https://www.nice.org.uk/guidance/ng188
- Singh D. Practical encyclopedia of oriental therapy. Acupuncture and moxotherapy. Moscow: OOO “Izdatelstvo AST-LTD”; 1997. (In Russ).
- Dubrovin D, Upur H. Theory and practice of classical Chinese medicine. Volume 1. Fundamentals of Chinese medicine. Saint Petersburg: “Humanitarian Academy”; 2021. (In Russ).
- Tykochinskaya ED. Basics of acupuncture. Moscow: “Medicine”; 1979. (In Russ).
- Hecker HU, Stivling A, Peke ET, Kastner J. Acupuncture: A Practical Guide / Trans. from English – 2nd ed. Moscow: MEDpress-inform; 2021. (In Russ).
- Seon C, Lee DH, Kwon B-I. et al. Neural mechanisms of acupuncture for peripheral facial nerve palsy: A protocol for systematic review and meta analysis. Medicine (Baltimore). 2023; 102(18). doi: 10.1097/MD.0000000000015566.
- Andreeva GO. New technique of acupuncture in case of neuropathy of the facial nerve. Vestn. St. Petersburg un-ta. 2010;11(4): 36-41.
- Finsterer J, Scorza FA. Guillain-barre syndromein 220 patients with COVID-19. Egypt J Neurol Psychiatr Neurosurg. 2021;57(1):1–7. doi: 10.1186/S41983-021-00310-7.
- Cabrera Muras A, Carmona-Abell an MM, CollíaFern_andez A. et al. Bilateral facial nerve palsy associated with COVID-19 and Epstein-Barr virus co-infection. Eur Neurol J 2021;28(1):358–360.
- Helbok R, Beer R., LCoscher W. et al. Guillain-Barre syndrome in a patient with antibodies against SARS-COV-2. Eur Neurol J. 2020;27(9):1754-1756.
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