A clinical case of isolated non-compact left ventricular myocardium in a 29-year-old patient

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BACKGROUND: Non-compact left ventricular myocardium is a rare heterogeneous pathology, which in the two-layer structure of the myocardium. There is no generally accepted definition of this form of pathology for both echocardiography and cardiac magnetic resonance imaging. Non-compact left ventricular myocardium can occur at any age and is often asymptomatic. Treatment of non-compact left ventricular myocardium is nonspecific and symptomatic.

DESCRIPTION: This study describes a clinical case of a young patient who was diagnosed with non-compact left ventricular myocardium. The disease debuted in the form of cardiac arrhythmia. Holter monitoring showed frequent ventricular extrasystole and atrioventricular block of the first and second degrees. Moreover, echocardiography revealed a decrease in global contractile function of the left ventricle. The diagnosis was made after magnetic resonance imaging of the heart, which revealed the presence of non-compact myocardium of the anterior, lateral, and inferior walls of the left ventricle in the apical and middle segments. Sustained rhythm disturbances were not induced in electrophysiological research by rapid and programmed stimulation. The patient was prescribed antiarrhythmic therapy, followed by echocardiography Holter monitoring. In the future, the patient needs regular monitoring by a cardiologist.

CONCLUSION: Non-compact left ventricular myocardium should be diagnosed at an early stage, so that life expectancy can be increased owing to timely treatment of heart failure and the use of oral anticoagulants, antiarrhythmic drugs, cardiac resynchronization therapy, cardioverter-defibrillator implantation, and heart transplantation when other treatment options are ineffective.

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作者简介

Amina Alieva

N.I. Pirogov Russian National Research Medical University

编辑信件的主要联系方式.
Email: amisha_alieva@mail.ru
ORCID iD: 0000-0001-5416-8579
SPIN 代码: 2749-6427

MD, Cand. Sci. (Medicine), associate professor

俄罗斯联邦, Moscow

Irina Kovtyukh

N.I. Pirogov Russian National Research Medical University

Email: nurzhanna@yandex.ru
ORCID iD: 0000-0002-9176-1889
SPIN 代码: 4746-3716
俄罗斯联邦, Moscow

Natalia Teplova

N.I. Pirogov Russian National Research Medical University

Email: teplova.nv@yandex.ru
ORCID iD: 0000-0002-7181-4680
SPIN 代码: 9056-1948

MD, Dr. Sci. (Medicine), professor

俄罗斯联邦, Moscow

Kira Voronkova

N.I. Pirogov Russian National Research Medical University

Email: kiravoronkova@yandex.ru
ORCID iD: 0000-0003-1111-6378
SPIN 代码: 1636-7627

MD, Dr. Sci. (Medicine), professor

俄罗斯联邦, Moscow

Elena Reznik

N.I. Pirogov Russian National Research Medical University

Email: elenaresnik@gmail.com
ORCID iD: 0000-0001-7479-418X
SPIN 代码: 3494-9080
Researcher ID: N-6856-2016

MD, Dr. Sci. (Medicine), professor

俄罗斯联邦, Moscow

Irina Baykova

N.I. Pirogov Russian National Research Medical University

Email: 1498553@mail.ru
ORCID iD: 0000-0003-0886-6290
SPIN 代码: 3054-8884

MD, Cand. Sci. (Medicine), associate professor

俄罗斯联邦, Moscow

Gayane Totolyan

N.I. Pirogov Russian National Research Medical University

Email: tgg03@mail.ru
ORCID iD: 0000-0002-9922-5845
SPIN 代码: 1441-7740

MD, Cand. Sci. (Medicine), associate professor

俄罗斯联邦, Moscow

Vitaliy Timofeev

N.I. Pirogov Russian National Research Medical University

Email: timofeev_vt@rsmu.ru
ORCID iD: 0000-0002-3805-5942
SPIN 代码: 2323-5061

MD, Dr. Sci. (Medicine), associate professor

俄罗斯联邦, Moscow

Irina Kotikova

N.I. Pirogov Russian National Research Medical University

Email: kotikova.ia@mail.ru
ORCID iD: 0000-0001-5352-8499
SPIN 代码: 1423-7300
俄罗斯联邦, Moscow

Igor Nikitin

N.I. Pirogov Russian National Research Medical University

Email: igor.nikitin.64@mail.ru
ORCID iD: 0000-0003-1699-0881
SPIN 代码: 3595-1990

MD, Dr. Sci. (Medicine), professor

俄罗斯联邦, Moscow

参考

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2. Fig. 1. Electrocardiogram Holter monitoring 30.01.2024.

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3. Fig. 2. MRI of the heart, cinema mode, SSFP sequence (short axis) in a patient with non-compact myocardium. The arrows (→) indicate an increase in the trabecularity of the left ventricular myocardium in the middle lateral and lower segments, the arrow (⭤ ) shows a thickening of the non-compact layer.

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