The risk of affective disorders in COVID-19 recovered students
- 作者: Akimova D.D.1, Osipova N.N.1, Bardenshtein L.M.1, Dmitrieva E.V.2, Averina A.P.2
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隶属关系:
- Russian University of Medicine
- Smolensk State Medical University
- 期: 卷 30, 编号 6 (2024)
- 页面: 562-570
- 栏目: Original Research Articles
- ##submission.dateSubmitted##: 18.05.2024
- ##submission.dateAccepted##: 01.10.2024
- ##submission.datePublished##: 29.12.2024
- URL: https://medjrf.com/0869-2106/article/view/632190
- DOI: https://doi.org/10.17816/medjrf632190
- ID: 632190
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详细
BACKGROUND: The annual increase in patients with symptoms of affective disorders caused by COVID-19 highlights the need to investigate this issue.
AIM: To investigate the risk of COVID-19 consequences presented with symptoms of affective disorders in students of higher education institutions.
MATERIALS AND METHODS: The study included 131 female (n=89) and male (n=42) students of higher education institutions aged 18 to 31 years. All participants had COVID-19 (U04.9, U07.1, U07.2) and were not diagnosed with any mental disorder (ICD-10 codes F00–F99). Clinical psychophysiological and psychometric evaluation techniques, as well as descriptive statistics were used.
RESULTS: Most students (75.6%, n=99) in the study group had a mild infection. Female and male students had psychophysiological COVID-19 consequences of asthenia (77.9% of participants, n=102) and cognitive decline (54.2%, n=71). Affective disorders were diagnosed in 40.4% female participants, symptoms of mood disorders were much less frequent in men. Post-COVID-19 hypochondriac thoughts were found to be more common in women. Among all respondents, COVID-19 consequences of psychophysiological symptoms not only occurred within the first weeks after the viral disease, but also persisted for several months (in 36.6% of respondents, n=48), without resulting in an affective disorder. Psychometric evaluation techniques (State-Trait Anxiety Inventory, Hypomania Checklist, Beck Depression Inventory) revealed higher anxiety and cyclothymic mood swings in female and male students.
CONCLUSION: In COVID-19 recovered students without prior affective disorder, the most common disease consequences were asthenic symptoms (men and women were equally affected). Cyclothymic mood swings were noted, with a higher prevalence in women. Additional psychometric evaluation techniques found that state and trait anxiety in men and women was moderate, with women being more prone to depression.
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作者简介
Darya Akimova
Russian University of Medicine
Email: darja_akimova@rambler.ru
ORCID iD: 0009-0006-0305-8410
SPIN 代码: 8310-7650
俄罗斯联邦, Moscow
Natalia Osipova
Russian University of Medicine
编辑信件的主要联系方式.
Email: natinen@yandex.ru
ORCID iD: 0000-0002-8034-4457
SPIN 代码: 7532-4382
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, MoscowLeonid Bardenshtein
Russian University of Medicine
Email: barden@mail.ru
ORCID iD: 0000-0002-1171-5517
SPIN 代码: 9289-9177
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, MoscowElena Dmitrieva
Smolensk State Medical University
Email: vernulas@mail.ru
ORCID iD: 0000-0003-1551-6563
SPIN 代码: 8720-7068
俄罗斯联邦, Smolensk
Alexandra Averina
Smolensk State Medical University
Email: avexsa@mail.ru
ORCID iD: 0009-0002-8944-6043
SPIN 代码: 5311-3437
俄罗斯联邦, Smolensk
参考
- Deng J, Zhou F, Hou W, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: A meta-analysis. Ann N Y Acad Sci. 2021;1486(1):90–111. doi: 10.1111/nyas.14506
- Samushiya MA, Kryzhanovskiy SM, Ragimova AA, et al. COVID-19 effect on mental health and sleep disorders. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(4-2):49–54. EDN: ZYNNVN doi: 10.17116/jnevro202112104249
- Silva E de, Ono BH, Souza JC. Sleep and immunity in times of COVID-19. Rev Assoc Med Bras (1992). 2020;66(Suppl. 2):143–147. doi: 10.1590/1806-9282.66.S2.143
- Iznak AF, Iznak EV, Damyanovich EV, Oleichik IV. EEG correlates of suicidal intentions in depressive patients who survived and have not been ill with COVID-19. Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(11-2):92–95. EDN: KCCRNF doi: 10.17116/jnevro202312311292
- Mao L, Jin H, Wang M, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683–690. doi: 10.1001/jamaneurol.2020.1127
- Helms J, Kremer S, Merdji H, et al. Neurologic features in severe SARS-COV-2 infection. N Engl J Med. 2020;382(23):2268–2270. doi: 10.1056/NEJMc2008597
- Moriguchi T, Harii N, Goto J, et al. A first case of meningitis/encephalitis associated with SARS-coronavirus-2. Int J Infect Dis. 2020;94:55–58. doi: 10.1016/j.ijid.2020.03.062
- Ellul MA, Benjamin L, Singh B, et al. Neurological associations of COVID-19. Lancet Neurol. 2020;19(9):767–783. doi: 10.1016/S1474-4422(20)30221-0
- Wenting A, Gruters A, van Os Y, et al. COVID-19 neurological manifestations and underlying mechanisms: a scoping review. Front Psychiatry. 2020;11:860. doi: 10.3389/fpsyt.2020.00860
- Gromova OA, Torshin IY, Semenov VA, et al. Direct and indirect neurological manifestations of COVID-19. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(11):11–21. EDN: WOWGDZ doi: 10.17116/jnevro202012011111
- Kim Y, Bitna-Ha, Kim SW, et al. Post-acute COVID-19 syndrome in patients after 12 months from COVID-19 infection in Korea. BMC Infect Dis. 2022;22(1):93. doi: 10.1186/s12879-022-07062-6
- Hossain MM, Sultana A, Purohit N. Mental health outcomes of quarantine and isolation for infection prevention: a systematic umbrella review of the global evidence. Epidemiol Health. 2020;42:e2020038. doi: 10.4178/epih.e2020038
- Bakioğlu F, Korkmaz O, Ercan H. Fear of COVID-19 and positivity: mediating role of intolerance of uncertainty, depression, anxiety, and stress. Int J Ment Health Addict. 2021;19(6):2369–2382. doi: 10.1007/s11469-020-00331-y
- Oskolkova SN. Out-patient cases of mental disorders in COVID-19. Psychiatry (Moscow). 2020;18(3):49–57. EDN: UCCRRN doi: 10.30629/2618-6667-2020-18-3-49-57
- Malykhin F.T. COVID-19 in medical students: acute phase clinical manifestations and post-COVID syndrome. Mezhdunarodnyi zhurnal serdtsa i sosudistykh zabolevanii. 2022;10(33.1):38–43. EDN: PJJTCE doi: 10.24412/2311-1623-2022-33.1-38-43
- Prokhorov PYu, Putilin LV, Kozhevnikova TN. Psychoemotional status of medical students after COVID-19. Journal of New Medical Technologies. 2023;30(3):23–25. EDN: KVEMQK doi: 10.24412/1609-2163-2023-3-23-25
- Fu W, Yan S, Zong Q, et al. Mental health of college students during the COVID-19 epidemic in China. J Affect Disord. 2021;280(Pt A):7–10. doi: 10.1016/j.jad.2020.11.032
- Majumdar P, Biswas A, Sahu S. COVID-19 pandemic and lockdown: cause of sleep disruption, depression, somatic pain, and increased screen exposure of office workers and students of India. Chronobiol Int. 2020;37(8):1191–1200. doi: 10.1080/07420528.2020.1786107
- Odriozola-González P, Planchuelo-Gómez Á, Irurtia MJ, de Luis-García R. Psychological effects of the COVID-19 outbreak and lockdown among students and workers of a Spanish university. Psychiatry Res. 2020;290:113108. doi: 10.1016/j.psychres.2020.113108
- Son C, Hegde S, Smith A, et al. Effects of COVID-19 on college students' mental health in the United States: interview survey study. J Med Internet Res. 2020;22(9):e21279. doi: 10.2196/21279
- Kvaal K, Ulstein I, Nordhus IH, Engedal K. The Spielberger State-Trait Anxiety Inventory (STAI): the state scale in detecting mental disorders in geriatric patients. Int J Geriatr Psychiatry. 2005;20(7):629–634. doi: 10.1002/gps.1330
- Mosolov SN, Ushkalova AV, Kostyukova EG, et al. Validation of the HCL-32 Russian version for detection of bipolar II disorder patients among those with diagnosis of recurrent depressive disorder. Social and Clinical Psychiatry. 2015;25(1):21–30. EDN: UIPELB
- Beck AT, Ward CH, Mendelson M, et al. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561–571. doi: 10.1001/archpsyc.1961.01710120031004
- Osipova NN, Bardenshteyn LM, Lyamets LL, Dmitrieva EV. Application of screening techniques for early diagnostics of bipolar afapplication of screening techniques for early diagnosis of a risk of bipolar disorder in adolescents. Bulletin of Siberian Medicine. 2022;21(2):105–114. EDN: PFKGEL doi: 10.20538/1682-0363-2022-2-105-114
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