Anticoagulant therapy in patients with atrial fibrillation: management of bleeding

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Abstract

Bleeding is the most common complication of long-term anticoagulant therapy. For patients with atrial fibrillation, it is important to consider the balance of hemorrhagic and thromboembolic risks in the event of bleeding since unreasonable withdrawal of anticoagulants can worsen the prognosis. The management of patients with hemorrhagic complications is determined according to the severity of bleeding, type of anticoagulant taken, and presence of high thromboembolic risk factors. The paper presents the author’s protocol for the management of patients with atrial fibrillation and various types of hemorrhagic complications against the background of anticoagulant therapy.

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About the authors

Irina V. Zotova

Center for Individualized Prevention and Treatment of Arterial and Venous Thrombosis, City Clinical Hospital Nо 17; Central State Medical Academy of department of presidential affairs of Russian Federation

Author for correspondence.
Email: irinazotova@bk.ru
ORCID iD: 0000-0001-8309-8231

MD, Cand. Sci. (Med.)

Russian Federation, 21 Marshala Timoshenko st., 121359, Moscow; Moscow

References

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Supplementary files

Supplementary Files
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1. Fig. General principles for the management of bleeding in patients receiving oral anticoagulants. VKA, vitamin K antagonists; AC, anticoagulants; DOAC, direct oral anticoagulants; FFP, fresh frozen plasma; INR, international normalized ratio; PRC, packed red cells.

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