The lacunar infarction



Cite item

Full Text

Abstract

The article considers pathogenic, clinical and therapeutic aspects of lacunar infarctions. It is emphasized that the source of their occurrence can be found in arterial hypertension, affection of arterioles supplying blood to remote section of cerebral hemispheres and brain trunk as well. The description of clinical characteristics of main lacunar syndromes (purely locomotor stroke, purely sensitive stroke, sensorimotor stroke, ataxic hemiparesis, syndrome of dysarthria and inept hand) is given. The recommendations on treatment and prevention of lacunar infarction are proposed.

Full Text

Лакунарный инфаркт
×

About the authors

Maksim Alekseevich Domashenko

The research center of neurology of of the Russian academy of medical sciences

Email: mdomashenko@gmail.ru
Moscow, Russia

Anna Igorevna Damulina

The research center of neurology of of the Russian academy of medical sciences

Moscow, Russia

References

  1. Верещагин Н. В., Моргунов В. А., Гулевская Т. С. Патология головного мозга при атеросклерозе и артериальной гипертонии. М.: Медицина; 1997.
  2. Максимова М. Ю. Малые глубинные инфаркты головного мозга при артериальной гипертонии и атеросклерозе: Автореф. дис.. д-ра мед. наук. М.; 2002.
  3. Моргунов В. А., Гулевская Т. С. Малые глубинные инфаркты головного мозга при артериальной гипертонии и атеросклерозе. Архив патологии. 1994; 2: 33—8.
  4. Суслина З. А., Танашян М. М., Домашенко М. А. Антитромботическая терапия ишемических нарушений мозгового кровообращения. М.: МИА; 2009: 133—56.
  5. Суслина З. А., Пирадов М. А. Инсульт: диагностика, лечение, профилактика. M.: МЕДпресс-информ; 2009.
  6. Суслина З. А. Очерки ангионеврологии. М.: Атмосфера; 2005: 53—6.
  7. Шевченко Ю. Л., Кузнецов А. Н., Виноградов О. И. Лакунарный инфаркт головного мозга. М.: РАЕН; 2011.
  8. Фонякин А. В., Гераскина Л. А. Современные стратегии вторичной профилактики ишемического инсульта. Consilium medicum. 2011; 2, прил.: 17—21.
  9. Adibhatla R. M., Hatcher J. F. Role of lipids in brain injure and diseases. Future Lipidol. 2007; 2: 403—22.
  10. Bamford J. M., Warlow C. P. Evolution and testing of the lacunar hypothesis. Stroke. 1988; 19: 1074—82.
  11. Bogousslavsky J. Risk factors stroke prevention. European Stroke Initiative (EUSI). Cerebrovasc. Dis. 2000; 10 (Suppl. 3): 12—21.
  12. Chamorro A., Sacco R. L., Mohr J. P. et al. Clinical-computed tomographic correlations of lacunar infarction in The Stroke Data Bank. Stroke. 1991; 22: 175—81.
  13. Chabriat H. Clinical spectrum of CADASIL: a study of 7 families. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Lancet. 1995; 346: 934—9.
  14. Chinese Acute Stroke Trial Collaborative Group. CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. CAST (Chinese Acute Stroke Trial) Collaborative Group. Lancet. 1997; 349 (9066): 1641—9.
  15. Donnan G. A. A prospective study of lacunar infarction using computerized tomography. Neurology. 1982; 32: 49—56.
  16. Donnan G. A., Norrving B., Bamford J. et al. Subcortical infarction: classification and terminology. Cerebrovasc. Dis. 1993; 3: 248— 51.
  17. Donnan G. A. Subcortical stroke. Oxford: Oxford University Press; 2002.
  18. Fisher C. M. Ataxic hemiparesis. A pathologic study. Arch. Neurol. 1978; 35: 126—8.
  19. Fisher C. M. Homolateral ataxia and crural paresis: a vascular syndrome. J. Neurol. Neurosurg. Psychiatry. 1965; 28: 48—55.
  20. Fisher C. M. Lacunar strokes and infarcts: a review. Neurology. 1982; 32: 871—6.
  21. Fisher C. M. Lacunar infarcts: a review. Cerebrovasc. Dis. 1991; 1: 311—20.
  22. Fisher C. M. Pure sensory stroke involving face, arm, and leg. Neurology. 1965; 15: 76—80.
  23. Fisher C. M. Lacunes: small, deep cerebral infarcts. Neurology. 1965; 15: 774—84.
  24. Fisher C. M., Curry H. B. Pure motor hemiplegia of vascular origin. Arch. Neurol. 1965; 13: 30—44.
  25. Gautier J. C. Atherosclerotic lesions and mechanisms of cerebral ischaemia. Eur. Neurol. 1978; 17 (Suppl. 1): 27—30.
  26. Gan R., Sacco R. L. Testing the validity of the lacunar hypothesis: the Northern Manhattan Stroke Study experience. Neurology. 1997; 48: 1204—11.
  27. Grau-Olivares M. Neuropsychological abnormalities associated with lacunar infarction. J. Neurol. Sci. 2007; 257: 160—5.
  28. Giroud M. Natural history of lacunar syndromes. Contribution of the Dijon registry of cerebrovascular complications. Rev. Neurol. (Paris). 1991; 147: 566—72.
  29. Hackman D. G., Spence J. D. Combining multiple approaches for the secondary prevention of vascular events after stroke. A quantitative modeling study. Stroke. 2007; 38: 1881—5.
  30. International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group. Lancet. 1997; 349 (9065): 1569—81.
  31. Joutel A. Notch 3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature. 1996; 383: 707—10.
  32. Wada M., Nagasawa H., Kurita K. et al. Cerebral small vessel disease and C-reactive protein: results of a cross-sectional study in community-based Japanese elderly. Neurol. Sci. 2008; 264: 43—9.
  33. Longstreth W. J. Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: the Cardiovascular Health Study. Arch. Neurol. 1998; 55: 1217—25.
  34. Mohr J. P. The Harvard Cooperative Stroke Registry: a prospective registry. Neurology. 1978; 28: 754—62.
  35. Mohr J. P. Lacunes. Stroke. 1982; 13: 3—11.
  36. Mohr J. P., Marti-Vilalta J. L. Stroke. Philadelphia: Churchill-Livingstone; 1998.
  37. Mori E., Yamadori A., Kudo Y. Ataxic hemiparesis from small capsular hemorrhage. Computed tomography and somatosensory evoked potentials. Arch. Neurol. 1984; 41: 1050—3.
  38. Mizon J. P., Rosa A. Predominantly crural hemiparesis and ipsilateral ataxia caused by meningioma of the falx cerebri. Rev. Neurol. (Paris). 1986; 142: 68—9.
  39. Melo T. P. Pure motor stroke: a reappraisal. Neurology. 1992; 42: 789—95.
  40. Nikolaos I. H. Lacunar syndrome. Medicine Neurology. 2011 www. medscape.com.
  41. Poirier J., Derouesné C. The concept of cerebral lacunae from 1838 to the present. Rev. Neurol. (Paris). 1985; 141: 3—17.
  42. Poirier J., Derouesne C. Cerebral lacunae: a proposed new classification. Clin. Neuropathol. 1984; 3: 266—8.
  43. Rashid R. Blood pressure reduction and secondary prevention of stroke and other vascular events. A systematic review. Stroke. 2003; 34: 2741—9.
  44. Sanguineti I. Ataxic hemiparesis syndrome: clinical and CT study of 20 new cases and review of the literature. Italy J. Neurol. Sci. 1986; 7: 51—9.
  45. Schrader J. S. Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention principal results of a prospective randomized controlled study (MOSES). Stroke. 2005; 36: 1218—26.
  46. Stein R. W. Caudate hemorrhage. Neurology. 1984; 34: 1549—54.
  47. Tuszynski M. H., Petito C. K., Levy D. E. Risk factors and clinical manifestations of pathologically verified lacunar infarctions. Stroke. 1989; 20: 990—9.
  48. The American Heart Association/American Stroke Association (AHA/ASA): Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack 2010. Stroke. 2011; 42: 227—276.
  49. The European Stroke Organization (ESO) Executive Committee and the ESO Writing Commitee: Guidelines for management of ischaemic stroke and transient ischaemic attacks 2008. Cerebrovasc. Dis. 2008; 25: 457—507.
  50. Warlow C. P., Dennis M. S. Stroke. A practical guide to management. Oxford: Blackwell Science; 1996: 123—7.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2013 Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия  ПИ № ФС 77 - 86296 от 11.12.2023 г. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80632 от 15.03.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies