Vol 18, No 4 (2012)

The article deals with the assessment of effectiveness of application of heated oxygen helium mixture (thermogeliox) as combined with the nebulizer therapy in complex treatment of patients with bronchial asthma. The examined sample consisted of 80 patients with bronchial asthma of moderate and severy degree at exacerbation phase of disease. The complex treatment with thermogeliox was applied to 40 patients of main group. The single session of combined application of thermogeliox and nebulizer therapy to patients with bronchial asthma reliably improves the bronchial patency and results in significantly increases saturation of blood with oxygen in patients with bronchial asthma of severe degree. The complex treatment with thermogeliox of patients with bronchial asthma of moderate and seveiy degree contributes to more evident improvement of clinical picture of disease as compared with standard treatment: reliable decrease of attacks of suffocation and stertor, relief of cough and dyspnea, improvement of indicators of pulmonary ventilation with reliable decrease of intensity of bronchial obstruction, significant increase of partial tension of blood oxygen and blood oxygenation. The highest effectiveness of complex treatment is noted in patients with severe form of bronchial asthma. Besides, a significant improvement of quality of life occurs against the background of tangible improvement of clinical functional indicators. The study results demonstrate the expedience of widespread application of thermogeliox combined with the nebulizer therapy for the purpose of increasing the effectiveness of rehabilitation treatment of patients with bronchial asthma.

При морфологическом исследовании секционного материала мышечной ткани диафрагмы и скелетной мускулатуры при ожирении выявлен ряд изменений в структуре волокон и системе кровообращения, особенно в микроциркуляторном русле. Во всех случаях основные патологические изменения в мышечной ткани проявлялись разволокнением миофибрилл и исчезновением поперечной исчерченности, истончением и деструкцией отдельных волокон с замещением фрагментов ткани жировыми клетками. Особенно это хорошо заметно в области микроциркуляторного русла, где сформировались островки жировой ткани, прослаивающие мышечные волокна, что, в свою очередь, приводило к снижению сократительной функции дыхательной мускулатуры.

The article deals with the actual issues of diagnostics and treatment of complications of parenteral drug addiction in conditions of surgery department. The sample of 517 cases of visiting doctors because the complications after parenteral introduction of handicraft narcotic drugs developed was analyzed. The classification of post-injection complications is developed considering the clinical symptomatology, treatment policy and rehabilitation prognosis within each form of complication. It is established that the occurrence of tissue ischemia against the background of parenteral introduction of drug substitutes is related very often not only to the main arteries thrombosis but to the spasm of arterioles and capillaries. The algorithm of diagnostics and treatment of post-injection complications in patients with drug addiction is developed.

The techniques of questionnaire and testing were applied to the sampling of 132 HIV-positive patients. The study revealed that persons with alcohol abuse consist from 32.6 to 53.8%. The clinically reliable symptoms were established among 29.6% of patients (19.7% of females and 39.4% of males). In favor of alcohol abuse indirectly testify tobacco smoking and diseases of liver (hepatitis, cirrhosis) and proper pathologic motivation of alcohol abuse. The HIV-positive patients suffering of alcohol abuse have worse prognosis of course of disease and they are less committed to anti-retrovirus treatment being the target risk group of infection spread.

The results of clinical laboratory, endoscopic and morphologic analyses in children with bronchial asthma and concurrent chronic gastritis demonstrated that the level of total IgE has no significant differences in groups of patients with different degree of Helicobacter contamination and with the absence of Helicobacter pilori. At that, in 78% of patients the IgE level significantly exceeded the normal values. In case of absence of Helicobacter pilori, the lymfo-follicular hyperplasia of mucous membrane of the stomach was detected only in 12% of patients and in presence of Helicobacter pilori in 58.3% of patients. This case is probably related to the intensity of local immune response to Helicobacter infection. In the group of children with bronchial asthma and Helicobacter pilori high contamination the exacerbation of chronic gastritis proceeded in a more severe form.