Vol 23, No 3 (2017)

The article presents results of analysis of the register of out-patients and in-patients with atrium fibrillation (n=1624) observed in 2009-2015. The retrospective data analysis and prospective observation of certain percentage of patients were applied to evaluate rate and conformity of implementation of various groups of anti-thrombotic medications in conditions of real practice of polyclinics and hospitals of Moscow. The results are compared with data of national studies of this issue during recent years.

The actual guidelines on treatment of pneumonia emphasize necessity of establishment of etiologic diagnosis for therapy rationale. The necessity occurs to group agents according significance of their effect at evaluating etiologic role of a number of agents, for instance under implementation of epidemiological investigations, studying of etiologic structure of infections, planning of medicinal support. In that case, the Fishburn method fits perfectly. The purpose of study is to implement Fishburn method in establishing role of traditional and atypical agents in etiologic structure of community-acquired pneumonia.Materials and methods. The sampling included 172 examined patients aged from 18 to 30 years being under hospital treatment with confirmed diagnosis of community-acquired pneumonia. The analysis was applied to such biologic substrates as phlegm, blood, lavage (bronchoalveolar fluid). The technique of polymerase chain reaction was used. To determine weight coefficients of every analyzed etiologic agents with their subsequent distribution according percentage in etiologic structure. The Fishburn method was applied. The results. The main agents were established Streptococcus pneumoniae (separated in 86,3% of patients) and Haemophilus influenzae (41,2%). The mixed infection occurred in 65.8% of examined patients. The most propagated are such associations as Streptococcus pneumoniae and Haemophilus influenzae, Streptococcus pneumoniae and M. pneumoniae. Conclusion. S. pneumoniae, H. influenzae, M. pneumoniae are independent infection agents related to high and average levels. In the most cases, the detected agents were found in associations. A significant rate of detection of Herpes simplex I/II (16,2%) in blood and saliva of patients with community-acquired pneumonia testifies weakening of immune system. Herpes simplex I/II worsens course of diseases but is not considered as independent infection agent. The data obtained has epidemiological significance and can impact on development of medication support.

The complex program of health promotion for university students with disorders of adaptation processes was developed. The program includes application of dynamic, isometric and breathing exercises at working table during micro-pauses for amelioration of cerebral blood circulation. Increasing of resistance of organism to shortage of oxygen and normalization of vegetative functions. The application of massage of biologically active points applied during scheduled breaks is addressed to optimizing functional conditions of students. The implementation of complex of common developing exercises, application of health promoting running and rainy shower in the end of training exercise is oriented on increasing physical readiness and stimulating students' own adaptive possibilities.The approbation of originally developed program demonstrated its good efficiency in adjustment of deadaptation disorders occurring in the process of education. The results of study demonstrated that in boys and girls after three-months health promoting training neuro-psychic tension decreased, resistance to stress impact increased and anxiety lessened. Simultaneously, increasing of number of students with high level of adaptation to actual social conditions was observed. The amelioration of vegetative resistance of organisms of students was noted. The testing of physical readiness demonstrated that in students, after correcting exercises, muscular strength of wrists increased, velocity force capacities and indices of force endurance in control exercise "jump-rope" ameliorated and suppleness and static resistance of organism. The application of proposed means of health promotion promoted mobilization of workability of nervous cells and nervous system that is substantiated by the results of tapping-test.The application of health promotion program resulted in increasing of academic progress in studies of boys and girls up to 0.4-0.7 points. The obtained data was used to recommend for implementing in educational institutions the developed program of health promoting student youth and minimizing deadaptation disorders occurring in student social environment.

The calcined aortic stenosis is one the most frequently occurring cardio-vascular diseases with unfavorable prognosis of course. The modern concepts about risk factors of development, pathogenesis and course of disease starting with inflammation and endothelial dysfunction and terminating with bone metaplasia permit determining prospective directions of deceleration of progression of calcined aortic stenosis. The high risk of unfavorable cardio-vascular occurrences associated with calcinosis of valvular apparatus of heart, availability of concomitant diseases making difficulties for correction of valvular impairments makes searching for causes of development and progression of ectopic calcification of aortic valve especially actual. The development of strategy of modification of risk factors and prevention of progression of early valvular impairments and blood circulation insufficiency are actual to the same extent. The review considers main clinical factors associated with development of calcined aortic stenosis, significance of genetic polymorphism in development of this heart disease and also main pathogenic mechanisms of its progressing.

More than 90% of all visits to children orthopedist is related to pathology of feet of children age, flat foot in particular. The review present actual data concerning classification, etiology and characteristics of pathological anatomy of disease, diagnostic techniques and features of gait. The data related to present methods of conservative and operational treatment of flat foot is presented.